Journal: Neoplasia (New York, N.Y.)

Article Title: Assessing axitinib-induced differential responses in tumor vascularization and oxygenation with combined optoacoustic angiography and diffuse optical spectroscopy

doi: 10.1016/j.neo.2026.101303

Figure Lengend Snippet: Axitinib inhibits Colo320 growth. ( a ) The experimental timeline: time points of axitinib administration are indicated by black triangles, time points of OA and DOS investigation - by white triangles, time point of morphological study – by red triangle. ( b ) Dynamics of the Colo320 tumor volumes during treatment with axitinib. Individual values, 25-75 percentiles, medians, minimum and maximum of the data set (n = 6). *, p < 0.05; **, p < 0.01 for treated versus control group (Wilcoxon test). # , p < 0.05 for current values versus initial level (Mann-Whitney test).

Article Snippet: All the experiments were conducted on subcutaneously implanted xenograft model based on the Colo320 colon adenocarcinoma cell line (Colo320DM, ATCC No CCL-220).

Techniques: Control, MANN-WHITNEY

Journal: Neoplasia (New York, N.Y.)

Article Title: Assessing axitinib-induced differential responses in tumor vascularization and oxygenation with combined optoacoustic angiography and diffuse optical spectroscopy

doi: 10.1016/j.neo.2026.101303

Figure Lengend Snippet: Axitinib-induced reduction of tumor vascularity. ( a ) Examples of OA images of Colo320 vasculature before and after treatment with axitinib. Bar is 3 mm. Dashed lines contour the tumor zones. ( b ) Volumetric vessel fraction of the Colo320 tumors during treatment with axitinib. ( c ) The corresponding projected vessel area. Individual values and M ± SD (n = 6). *, p < 0.05; **, p < 0.01 for treated versus control group (unpaired t-test). # , p < 0.05; # # , p < 0.01 for current values versus initial level (paired t-test).

Article Snippet: All the experiments were conducted on subcutaneously implanted xenograft model based on the Colo320 colon adenocarcinoma cell line (Colo320DM, ATCC No CCL-220).

Techniques: Control

Journal: Neoplasia (New York, N.Y.)

Article Title: Assessing axitinib-induced differential responses in tumor vascularization and oxygenation with combined optoacoustic angiography and diffuse optical spectroscopy

doi: 10.1016/j.neo.2026.101303

Figure Lengend Snippet: Axitinib-induced decreases of CD31 positive blood vessels. ( a ) Examples of microimages from the tumor sections (scale bar 100 µm). ( b ) The numbers of CD31+ microvessels in the untreated and axitinib-treated Colo320 tumors after immunohistochemical staining for CD31. Individual values and M ± SD. ***, p < 0.001 for treated versus control group (unpaired t-test). ( c ), The values of CD31+ microvessels versus vascular fraction in the treated and untreated tumors.

Article Snippet: All the experiments were conducted on subcutaneously implanted xenograft model based on the Colo320 colon adenocarcinoma cell line (Colo320DM, ATCC No CCL-220).

Techniques: Immunohistochemical staining, Staining, Control

Journal: Neoplasia (New York, N.Y.)

Article Title: Assessing axitinib-induced differential responses in tumor vascularization and oxygenation with combined optoacoustic angiography and diffuse optical spectroscopy

doi: 10.1016/j.neo.2026.101303

Figure Lengend Snippet: Axitinib-induced increase of pimonidazole-positive areas. ( a ) Examples of LSM images taken from the tumor sections. Bar 2 mm. ( b ) Relative hypoxic fraction (RHF) of the untreated and axitinib-treated Colo320 tumors after immunofluorescent staining for hypoxia with pimonidazole. Individual values and M ± SEM. *, p < 0.05 for treated versus control group (unpaired t-test). ( c ) The RHF values versus StO 2 .

Article Snippet: All the experiments were conducted on subcutaneously implanted xenograft model based on the Colo320 colon adenocarcinoma cell line (Colo320DM, ATCC No CCL-220).

Techniques: Staining, Control

Journal: Turkish Journal of Biochemistry

Article Title: Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells

doi: 10.1515/tjb-2023-0076

Figure Lengend Snippet: Figure 1: Dose–response curves and IC50 values of RSV COLO320 (A) and COLO741 (B) cells treated with different concentrations of RSV for 24 and 48 h, respectively.

Article Snippet: Cell lines and cell culture COLO320 (ATCC: CCL-220.1) and COLO741 (ECACC: 93052621) cell lines were used.

Techniques:

Journal: Turkish Journal of Biochemistry

Article Title: Resveratrol modulates miRNA machinery proteins in different types of colon cancer cells

doi: 10.1515/tjb-2023-0076

Figure Lengend Snippet: Figure 2: Immunoreactivity of CD-9 (A, B), CD-63 (C, D), Dicer (E, F), eIF2α (G, H), Ago2 (I, J), in control (A, C, E, G, I) and 25 μg/mL RSV-treated (B, D, F, H, J, L, N) COLO320 cells. Scale bars=20 μm.

Article Snippet: Cell lines and cell culture COLO320 (ATCC: CCL-220.1) and COLO741 (ECACC: 93052621) cell lines were used.

Techniques: Control